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Pancreatic Cancer

If you are having any symptoms or have any questions, please call 811 to speak with a registered nurse 24 hours a day.

What is pancreatic cancer?

Pancreatic cancer is a disease in which cancer cells form on your pancreas. Your pancreas is an organ. It is located behind your stomach and in front of your spine. Your pancreas produces juices that break down food and control blood sugar. Pancreatic cancer is difficult to diagnose early.

Symptoms of pancreatic cancer

Symptoms of pancreatic cancer include the following:

  • Jaundice (yellowing) of the skin and eyes.
  • Stomach pain.
  • Back pain.
  • Weight loss (without trying).
  • Poor appetite.
  • Dark, brown urine.
  • Light-colored or greasy stools (poop).
  • Itchy skin.
  • Nausea, vomiting.
  • Enlarged gallbladder or liver.
  • Blood clots.
  • Diabetes (it’s rare that pancreatic cancer causes diabetes if you didn’t already have it).

What causes pancreatic cancer?

No one knows what causes pancreatic cancer. There are certain risk factors. This includes:

  • smoking
  • Obesity
  • Inactivity
  • Age
  • Workplace exposure to chemicals
  • Gender
  • Race
  • Family history of inherited genetic syndromes. These include breast and ovarian cancer syndrome, breast cancer, familial atypical multiple mole melanoma, familial pancreatitis, Lynch syndrome, and Peutz-Jeghers syndrome.
  • Diabetes
  • Chronic pancreatitis (inflammation of the pancreas)
  • Unhealthy diet
  • Coffee
  • Alcohol
  • Certain infections (H. pylori or Hepatitis B)

How is pancreatic cancer diagnosed?

The pancreas is buried deep inside the body. This can make an early diagnosis difficult. If your healthcare provider suspects you have pancreatic cancer, they might do the following:

  • Perform a physical exam (your healthcare provider will feel your stomach for the presence of large tumors).
  • Order imaging tests. This can include an ultrasound, CT, MRI, or PET scan.
  • Order blood tests.
  • Do a biopsy (surgically remove a sample from the pancreas).

Can pancreatic cancer be prevented or avoided?

Pancreatic cancer cannot be prevented or avoided. However, you can make lifestyle changes to lower certain risk factors. Those include:

  • Get moving. Exercise daily. Strive for 20 to 30 minutes per day.
  • Stop smoking.
  • Limit alcohol.
  • Control your diabetes.
  • Lose weight.
  • Eat healthy.

Talk to your healthcare provider about any genetic risk factors you may have.

Pancreatic cancer treatment

Most pancreatic cancer cases are diagnosed late (Stage 4). This means they likely spread to other areas of the body. Depending on the stage of the cancer, surgery is possible.  There are five types of standard treatment used for pancreatic cancer:

  • Surgery: This involves removal of the tumor. In extreme cases it may mean removing the entire pancreas.
  • Radiation therapy: This uses high energy x-rays or other radiation to kill or slow the growth of cancer cells.
  • Chemotherapy: This therapy uses drugs to stop the growth of cancer cells.
  • Chemoradiation therapy: This combines chemotherapy and radiation therapy.
  • Targeted therapy: Drugs are used to identify and attack specific cancer cells. This is done to cause less harm to normal cells than chemotherapy or radiation

Living with pancreatic cancer

Pancreatic cancer is difficult to detect early. This is because it doesn’t always cause symptoms until after it has spread to other parts of the body. This means that by the time it is detected, the prognosis is often not good. As with any cancer, the survival rate changes depending on how early it is detected.

If pancreatic cancer is caught early enough, your healthcare provider will likely begin treating it with one of the treatments outlined above.

If the cancer is at a late stage, the focus will often be on palliative care. This means quality of life and end of life care. This goal is to make a person comfortable and pain free.

FOR MORE INFORMATION

Canadian Cancer Society 

https://www.cancer.ca/

This information provides a general overview and may not apply to everyone. Talk to your healthcare provider to find out if this information applies to you and to get more information on this subject.

This article was contributed by: familydoctor.org editorial staff

Copyright (c) by the American Academy of Family Physicians

Nova Scotia Telecare, Reviewed by Clinical Services Working Group, October 2025

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