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Metabolic Syndrome

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OVERVIEW

What is metabolic syndrome?

Metabolic syndrome is the term used to describe a set of risk factors for heart disease. These include high blood pressure, high cholesterol, and diabetes or high blood sugars.

What is insulin resistance?

Your body changes most of the food you eat into glucose (a form of sugar). Insulin is a hormone produced by the pancreas that allows glucose to enter all the cells of your body and be used as energy.

In some people, the body’s tissues stop responding to insulin. Healthcare providers refer to this condition as insulin resistance. If you have insulin resistance, your body will make more and more insulin, but because your tissues don’t respond to it, your body can’t use glucose properly.

 How does this relate to metabolic syndrome? Insulin resistance often goes along with other health problems, such as diabetes, high cholesterol and high blood pressure. These problems are all risk factors for heart disease. When a person has many of these problems at the same time, healthcare providers commonly call it “metabolic syndrome.” It is sometimes called “insulin resistance syndrome” or “syndrome X.” Many people who have type 2 diabetes also have metabolic syndrome.

SYMPTOMS

For the most part, metabolic syndrome does not have any true signs or symptoms. If you gain weight around your waist, it can be one indicator of metabolic syndrome.

But some of the other diseases that go along with metabolic syndrome do have symptoms. These include possible frequent urination and unusual thirst when you have diabetes.

CAUSES & RISK FACTORS

What causes metabolic syndrome?

A number of factors can act together to cause metabolic syndrome. A person who takes in too many calories and too much saturated fat, and does not get enough physical activity may develop metabolic syndrome. Other causes include insulin resistance and a family history of the risk factors for metabolic syndrome.

DIAGNOSIS & TESTS

How is metabolic syndrome diagnosed?

Your healthcare provider will do a physical exam and blood tests. They can diagnose metabolic syndrome if at least 3 of the following are true:

  • You are overweight or obese, and you carry the weight around your middle. For men, this means a waist that measures greater than or equal to 102 cm (40 inches) around. For women, it means a waist that measures greater than or equal to 88 cm (35 inches) around.
  • You have higher than normal blood pressure (130/85 mm Hg or greater).
  • You have high blood glucose levels (5.6 mmol/L or greater)
  • You have a higher than normal amount of fat in your blood (a triglyceride level of 1.7 mmol/L or greater).
  • You have a lower than normal high-density lipoprotein (HDL) cholesterol level (an HDL level less than 1.0 mmol/L). HDL cholesterol is the “good” cholesterol.

The more of these risk factors you have, the higher your risk of heart disease.

PREVENTION

Can metabolic syndrome be prevented or avoided?

A healthy lifestyle can help prevent metabolic syndrome. This includes losing weight if you’re overweight. It also includes getting more physical activity and eating a healthy diet. Also, if you smoke, you should stop.

TREATMENT

If you already have metabolic syndrome, making these healthy lifestyle choices can help reduce your risk of heart disease and other health problems. If lifestyle changes alone can’t control your risk factors for heart disease, such as high blood pressure, your healthcare provider may prescribe medicine to help.

Maintain a healthy weight

Your healthcare provider can measure your body mass index (BMI) to determine a healthy weight for your height. They can help you make a plan to lose weight if you’re overweight, and to maintain your weight through a healthy diet and regular physical activity. Carrying extra weight in your abdomen is especially unhealthy. Losing this weight or exchanging it for muscle weight will improve health.

Get more physical activity

Not being active is one of the biggest risk factors for heart disease. It’s important to get some kind of exercise on a regular basis. Start by contacting your healthcare provider, especially if you haven’t been active for a while. You may need to begin with some light exercise, such as walking. Then you can gradually increase how hard you exercise and for how long. A good goal for many people is to work up to exercising 4 to 6 times a week for 30 to 60 minutes at a time. A minimum of 150 minutes a week is best for good health. Your healthcare provider can help you set a goal that’s right for you.

Eat a healthy diet

When combined with exercise, a healthy diet can help you lose weight, lower your cholesterol level and improve the way your body functions. Foods high in dietary fiber should be a regular part of your diet. You should eat several servings of fruits, vegetables and whole-grain bread every day. Also, limit the amount of saturated fat, trans fat, sodium (salt) and added sugar in your diet.

Living with metabolic syndrome

Improving your heath through diet and exercise if often enough to prevent metabolic syndrome. You may also need to take medicine for diabetes, high cholesterol, and high blood pressure. Being proactive about your health will help reduce your risk for heart disease.

This information provides a general overview and may not apply to everyone. Talk to your healthcare provider to find out if this information applies to you and to get more information on this subject.

Contributed by familydoctor.org editorial staff.

Copyright (c) by the American Academy of Family Physicians

Nova Scotia Telecare, Reviewed by Clinical Services Working Group, February 2025.

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